Science Based Fitness

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What is Science Based Fitness?

Your free- source of information, news, and deep dive into the latest science in the world or fitness and health. We dive deep into the literature and debunk a lot of fake claims. Also, providing helpful tips and workouts to improve your health and quality of life. 

Saffron

Saffron

What are the health benefits of Saffron? 

Saffron

Possible cure for depression?

Saffron is a very costly spice, and also known as Saffron Crocus. An increasing number of studies shows a lot of benefits for saffron. More randomize, double-blind, placebo control trials are showing promising results in overall health including inflammation, stress, anxiety, depression, cancer prevention, increase libido, and weight loss. 

Known as the sunshine spice due it’s distant color and mood enhancing affects. Saffron is also a very powerful anti-oxidant, which may help prevent many different types of cancers.  Supplementing with 60mg of Saffron for 12 weeks shown significant reduction in weight, fasting triglycerides and increase fasting HDL levels. Saffron constitutes a promising nutraceutical option for adolescents and children with obesity and prediabetes. 

Saffron could be an alternative to other SSRI medications in reducing anxiety and depression symptoms with little to no side effects. More large scale data is required to prove saffron is similar to an SSRI. 

Saffron may play a crucial role in male reproductive health and erectile dysfunction. Although prediabetes is a major risk factor erectile dysfunction, saffron may have aphrodisiac-like properties. 

Enhance mood

Studies show that saffron may improve mood and sleep. 

Decrease inflammation

Among active young adults, Saffron has been shown in improve recovery and make workouts more enjoyable in males. 

Help with weight loss

Saffron may help reduce appetite, body mass index, waist circumference and fat mass. 

Science Based Review

We highly recommend the benefits of saffron with turmeric. 

The combination of saffron with the benefits and anti-inflammation properties of turmeric delivers the best potential of decreased inflammation elevated mood.

Saffron + Turmeric

Turmeric

Major benefits for brain and body health

Turmeric contains compounds called curcuminoids that’s been shown to reduce inflammation and pain. The most popular curcuminoid is curcumin, and it’s the main active ingredient in turmeric. 

Cinnamon

Anti-inflammatory, aid in metabolic disease and help lose weight

Cinnamon is a spice that’s been shown to improve cardiovascular biomarkers. There’s evidence to show that cinnamon is rich in polyphenols, and may have a beneficial effect on cardio metabolic health, cholesterol, stress and inflammation. 

Cardamom

May help with high blood pressure, weight loss, and infection

Cardamom may help lower blood pressure, improve digestive issues, and help immune function. Research shows a protective compound found in cardamom may help prevent cancers cells from forming or developing. When cardamom is paired with turmeric, data found the combination to be even more effective at preventing tumor growth. 

Check out other topics

achieve your goals faster

Beta-alanine

Increase performance and recovery

Cocoa and Muscle

Increase strength and fatigue 

Truth About Cholesterol

The truth about LDL cholesterol and how to lower it

NMN

Anti-aging and diabetes prevention

Taurine

Increase energy, performance, and increase fat loss. 

Fat burning
training

How do we lose fat and what’s the best way! 

Check out more

New articles weekly

References

  • Kotanidou EP, Tsinopoulou VR, Giza S, Ntouma S, Angeli C, Chatziandreou M, Tsopelas K, Tseti I, Galli-Tsinopoulou A. The Effect of Saffron Kozanis (Crocus sativus L.) Supplementation on Weight Management, Glycemic Markers and Lipid Profile in Adolescents with Obesity: A Double-Blinded Randomized Placebo-Controlled Trial. Children (Basel). 2023 Nov 15;10(11):1814. doi: 10.3390/children10111814. PMID: 38002905; PMCID: PMC10670718.
  • Tóth B, Hegyi P, Lantos T, Szakács Z, Kerémi B, Varga G, Tenk J, Pétervári E, Balaskó M, Rumbus Z, Rakonczay Z, Bálint ER, Kiss T, Csupor D. The Efficacy of Saffron in the Treatment of Mild to Moderate Depression: A Meta-analysis. Planta Med. 2019 Jan;85(1):24-31. doi: 10.1055/a-0660-9565. Epub 2018 Jul 23. PMID: 30036891.
  • El Midaoui A, Ghzaiel I, Vervandier-Fasseur D, Ksila M, Zarrouk A, Nury T, Khallouki F, El Hessni A, Ibrahimi SO, Latruffe N, Couture R, Kharoubi O, Brahmi F, Hammami S, Masmoudi-Kouki O, Hammami M, Ghrairi T, Vejux A, Lizard G. Saffron (Crocus sativus L.): A Source of Nutrients for Health and for the Treatment of Neuropsychiatric and Age-Related Diseases. Nutrients. 2022 Jan 29;14(3):597. doi: 10.3390/nu14030597. PMID: 35276955; PMCID: PMC8839854.
  • Lu C, Ke L, Li J, Zhao H, Lu T, Mentis AFA, Wang Y, Wang Z, Polissiou MG, Tang L, Tang H, Yang K. Saffron (Crocus sativus L.) and health outcomes: a meta-research review of meta-analyses and an evidence mapping study. Phytomedicine. 2021 Oct;91:153699. doi: 10.1016/j.phymed.2021.153699. Epub 2021 Aug 8. PMID: 34419735.
  • Shafiee M, Arekhi S, Omranzadeh A, Sahebkar A. Saffron in the treatment of depression, anxiety and other mental disorders: Current evidence and potential mechanisms of action. J Affect Disord. 2018 Feb;227:330-337. doi: 10.1016/j.jad.2017.11.020. Epub 2017 Nov 7. PMID: 29136602.
  • Seyedi-Sahebari S, Farhang S, Araj-Khodaei M, Akhondzadeh S, Naseri A, Sanaie S, Frounchi N. The Effects of Crocus sativus (Saffron) on ADHD: A Systematic Review. J Atten Disord. 2024 Jan;28(1):14-24. doi: 10.1177/10870547231203176. Epub 2023 Oct 21. PMID: 37864351.
  • Shafiee A, Jafarabady K, Seighali N, Mohammadi I, Rajai Firouz Abadi S, Abhari FS, Bakhtiyari M. Effect of Saffron Versus Selective Serotonin Reuptake Inhibitors (SSRIs) in Treatment of Depression and Anxiety: A Meta-analysis of Randomized Controlled Trials. Nutr Rev. 2024 Jun 24:nuae076. doi: 10.1093/nutrit/nuae076. Epub ahead of print. PMID: 38913392.
  • Cerdá-Bernad D, Costa L, Serra AT, Bronze MR, Valero-Cases E, Pérez-Llamas F, Candela ME, Arnao MB, Barberán FT, Villalba RG, García-Conesa MT, Frutos MJ. Saffron against Neuro-Cognitive Disorders: An Overview of Its Main Bioactive Compounds, Their Metabolic Fate and Potential Mechanisms of Neurological Protection. Nutrients. 2022 Dec 17;14(24):5368. doi: 10.3390/nu14245368. PMID: 36558528; PMCID: PMC9781906.
  • Goyal A, Raza FA, Sulaiman SA, Shahzad A, Aaqil SI, Iqbal M, Javed B, Pokhrel P. Saffron extract as an emerging novel therapeutic option in reproduction and sexual health: recent advances and future prospectives. Ann Med Surg (Lond). 2024 Apr 4;86(5):2856-2865. doi: 10.1097/MS9.0000000000002013. PMID: 38694315; PMCID: PMC11060205.
  • Lopresti AL, Smith SJ. An examination into the mental and physical effects of a saffron extract (affron®) in recreationally-active adults: A randomized, double-blind, placebo-controlled study. J Int Soc Sports Nutr. 2022 Jun 7;19(1):219-238. doi: 10.1080/15502783.2022.2083455. PMID: 35813851; PMCID: PMC9261746.
  • Kutbi EH, Sohouli MH, Fatahi S, Lari A, Shidfar F, Aljhdali MM, Alhoshan FM, Elahi SS, Almusa HA, Abu-Zaid A. The beneficial effects of cinnamon among patients with metabolic diseases: A systematic review and dose-response meta-analysis of randomized-controlled trials. Crit Rev Food Sci Nutr. 2022;62(22):6113-6131. doi: 10.1080/10408398.2021.1896473. Epub 2021 Mar 19. PMID: 33739219.
  • Sarmadi B, Musazadeh V, Dehghan P, Karimi E. The effect of cinnamon consumption on lipid profile, oxidative stress, and inflammation biomarkers in adults: An umbrella meta-analysis of randomized controlled trials. Nutr Metab Cardiovasc Dis. 2023 Oct;33(10):1821-1835. doi: 10.1016/j.numecd.2023.03.010. Epub 2023 Mar 18. PMID: 37500345.
  • Maierean SM, Serban MC, Sahebkar A, Ursoniu S, Serban A, Penson P, Banach M; Lipid and Blood Pressure Meta-analysis Collaboration (LBPMC) Group. The effects of cinnamon supplementation on blood lipid concentrations: A systematic review and meta-analysis. J Clin Lipidol. 2017 Nov-Dec;11(6):1393-1406. doi: 10.1016/j.jacl.2017.08.004. Epub 2017 Aug 12. PMID: 28887086.
  • Verma SK, Jain V, Katewa SS. Blood pressure lowering, fibrinolysis enhancing and antioxidant activities of cardamom (Elettaria cardamomum). Indian J Biochem Biophys. 2009 Dec;46(6):503-6. PMID: 20361714.
  • Das I, Acharya A, Berry DL, Sen S, Williams E, Permaul E, Sengupta A, Bhattacharya S, Saha T. Antioxidative effects of the spice cardamom against non-melanoma skin cancer by modulating nuclear factor erythroid-2-related factor 2 and NF-κB signalling pathways. Br J Nutr. 2012 Sep 28;108(6):984-97. doi: 10.1017/S0007114511006283. Epub 2011 Dec 19. PMID: 22182368.
  • Majdalawieh AF, Carr RI. In vitro investigation of the potential immunomodulatory and anti-cancer activities of black pepper (Piper nigrum) and cardamom (Elettaria cardamomum). J Med Food. 2010 Apr;13(2):371-81. doi: 10.1089/jmf.2009.1131. PMID: 20210607

Beta-Alanine

Beta- Alanine

Hello I’m Your new trainer

Beta- Alanine

Muscle and endurance supplement with new cognitive benefits for mental health. 

Studies show that supplementation with Beta-alanine increase performance for higher intensity training. Also, beta-alanine supports muscle growth by aiding in muscle recovery and repair. 

Recent data suggests that B-alanine can result in carnosine elevations in the brain, which appears supplementation may increase resilience to post-traumatic stress disorder, mild traumatic brain injury and heat stress. 

Save On Beta Alanine

Shop today!

Not just for exercise

More research suggest beta-alanine may help reduce anxiety, reduce aging, and protect against cognitive decline. 

Why should you take Beta Alanine?

Nothing Feels As Good As Being Fit

Beta- alanine promotes faster recovery between exercise or sets, and helps increase output. Beta-alanine is a precursor to carnosine, and carnosine reduces lactic acid accumulation in your muscles during exercise. Beta-alanine increases your time to exhaustion by reducing fatigue. During exercise, glucose is broken down. Muscle breakdown glucose into lactic acid and converts into lactate. Carnosine works as a buffer against acid by reducing lactate in the muscle. Since beta-alanine elevates carnosine, muscle experience less fatigue during training. 

Increase Recovery

While Training

Muscle Repair

Post exercise and recovery

Fat burning

Greater lean body mass

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Start working on your body today, and with our individual fitness program, already in 90 days you will see a totally different girl in the mirror.

References

  • Artioli GG, Gualano B, Smith A, Stout J, Lancha AH Jr. Role of beta-alanine supplementation on muscle carnosine and exercise performance. Med Sci Sports Exerc. 2010 Jun;42(6):1162-73. doi: 10.1249/MSS.0b013e3181c74e38. PMID: 20479615.
  • Cimadevilla-Fernández-Pola E, Martínez-Roldán C, Maté-Muñoz JL, Guodemar-Pérez J, Sánchez-Calabuig MA, García-Fernández P, Hervás-Pérez JP, Hernández-Lougedo J. Effects of β-Alanine Supplementation on Subjects Performing High-Intensity Functional Training. Nutrients. 2024 Jul 19;16(14):2340. doi: 10.3390/nu16142340. PMID: 39064783; PMCID: PMC11280034.
  • Saunders B, Elliott-Sale K, Artioli GG, Swinton PA, Dolan E, Roschel H, Sale C, Gualano B. β-alanine supplementation to improve exercise capacity and performance: a systematic review and meta-analysis. Br J Sports Med. 2017 Apr;51(8):658-669. doi: 10.1136/bjsports-2016-096396. Epub 2016 Oct 18. PMID: 27797728.
  • Ostfeld I, Hoffman JR. The Effect of β-Alanine Supplementation on Performance, Cognitive Function and Resiliency in Soldiers. Nutrients. 2023 Feb 19;15(4):1039. doi: 10.3390/nu15041039. PMID: 36839397; PMCID: PMC9961614.
  • Hobson RM, Saunders B, Ball G, Harris RC, Sale C. Effects of β-alanine supplementation on exercise performance: a meta-analysis. Amino Acids. 2012 Jul;43(1):25-37. doi: 10.1007/s00726-011-1200-z. Epub 2012 Jan 24. PMID: 22270875; PMCID: PMC3374095.
  • Trexler ET, Smith-Ryan AE, Stout JR, Hoffman JR, Wilborn CD, Sale C, Kreider RB, Jäger R, Earnest CP, Bannock L, Campbell B, Kalman D, Ziegenfuss TN, Antonio J. International society of sports nutrition position stand: Beta-Alanine. J Int Soc Sports Nutr. 2015 Jul 15;12:30. doi: 10.1186/s12970-015-0090-y. PMID: 26175657; PMCID: PMC4501114.
  • Bellinger PM. β-Alanine supplementation for athletic performance: an update. J Strength Cond Res. 2014 Jun;28(6):1751-70. doi: 10.1519/JSC.0000000000000327. PMID: 24276304.
  • Georgiou GD, Antoniou K, Antoniou S, Michelekaki EA, Zare R, Ali Redha A, Prokopidis K, Christodoulides E, Clifford T. Effect of Beta-Alanine Supplementation on Maximal Intensity Exercise in Trained Young Male Individuals: A Systematic Review and Meta-Analysis. Int J Sport Nutr Exerc Metab. 2024 Jul 19;34(6):397-412. doi: 10.1123/ijsnem.2024-0027. PMID: 39032921.
  • Huerta Ojeda Á, Tapia Cerda C, Poblete Salvatierra MF, Barahona-Fuentes G, Jorquera Aguilera C. Effects of Beta-Alanine Supplementation on Physical Performance in Aerobic-Anaerobic Transition Zones: A Systematic Review and Meta-Analysis. Nutrients. 2020 Aug 19;12(9):2490. doi: 10.3390/nu12092490. PMID: 32824885; PMCID: PMC7551186.
  • Maté-Muñoz JL, Lougedo JH, Garnacho-Castaño MV, Veiga-Herreros P, Lozano-Estevan MDC, García-Fernández P, de Jesús F, Guodemar-Pérez J, San Juan AF, Domínguez R. Effects of β-alanine supplementation during a 5-week strength training program: a randomized, controlled study. J Int Soc Sports Nutr. 2018 Apr 25;15:19. doi: 10.1186/s12970-018-0224-0. PMID: 29713250; PMCID: PMC5918575.
  • Ostfeld I, Ben-Zeev T, Zamir A, Levi C, Gepner Y, Springer S, Hoffman JR. Role of β-Alanine Supplementation on Cognitive Function, Mood, and Physical Function in Older Adults; Double-Blind Randomized Controlled Study. Nutrients. 2023 Feb 12;15(4):923. doi: 10.3390/nu15040923. PMID: 36839281; PMCID: PMC9960300.

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Cocoa Can Save Your Life

Cocoa Powder

Health Benefits

Cocoa_Powder

Cocoa Powder

Why should you add it to your diet

Cocoa Powder might be a great addition to your diet to improve your health. Cocoa contains polyphenols, which are naturally occurring antioxidants. Cocoa also contains flavanols, and data shows that flavanols can reduce inflammation. 

Theobromine

And other Anti-oxidants

Theobromine found in cocoa is a natural alkaloid. Similar to caffeine’s affect on adenosine to make us feel more awake and alert, theobromine works similarly without  the jitters or stimulating affects of caffeine. Theobromine provides neuroprotection against age-related cognitive impairments such as Alzheimer’s and Parkinson’s disease. In regards to weight loss, theobromine enhances fat breakdown and contributes to weight reduction.   The benefits of theobromine include: 

Summary of benefits

Take the first step to your healthiest self.

Cocoa powder is rich in vitamins and minerals such as zinc, magnesium, selenium, iron, and more. Studies suggest that cocoa powder is rich in polyphenols, which are naturally occurring antioxidants. Cocoa also contains flavanols, and data shows that flavanols can reduce inflammation. In addition to anti-oxidants, cocoa contains theobromine. Theobromine is generally safe for human consumption and provides preventive and therapeutic effects in brain diseases such as stroke, depression, and Alzheimer’s. Another benefit to theobromine is to help regulate immune function, promote fat metabolism, and maintain cardiovascular health. 

Best way to eat cocoa Power?

eat delicious while burning extra fat

Cocoa powder should be at least 75% cocoa. However, data suggests a higher percentage promotes better health outcomes. You can add cocoa powder to smoothies, cereals, oatmeal, baked goods, pancakes, coffee, yogurt, mix with peanut butter or add to fruit.

References


  • Journal Article A Hahn, Joshua A Virk, Hafeez Ul Hassan A Wang, Zhen A Tang, Wai Hong WA Krittanawong, Chayakrit
     T Abstract 14006: Cardiovascular Health Benefits of Theobromine in Cacao and Chocolate D 2021 J Circulation P A14006-A14006 V 144 N Suppl_1 R doi:10.1161/circ.144.suppl_1.14006 U https://www.ahajournals.org/doi/abs/10.1161/circ.144.suppl_1.14006
  • Mengjuan Zhang, Haifeng Zhang, Lu Jia, Yi Zhang, Runwen Qin, Shihua Xu, Yingwu Mei,
    Health benefits and mechanisms of theobromine,
    Journal of Functional Foods,
    Volume 115, 2024, 106126,
    ISSN 1756-4646, https://doi.org/10.1016/j.jff.2024106126.
  • Martínez-Pinilla E, Oñatibia-Astibia A, Franco R. The relevance of theobromine for the beneficial effects of cocoa consumption. Front Pharmacol. 2015 Feb 20;6:30. doi: 10.3389/fphar.2015.00030. PMID: 25750625; PMCID: PMC4335269.
  • Fusar-Poli L, Gabbiadini A, Ciancio A, Vozza L, Signorelli MS, Aguglia E. The effect of cocoa-rich products on depression, anxiety, and mood: A systematic review and meta-analysis. Crit Rev Food Sci Nutr. 2022;62(28):7905-7916. doi: 10.1080/10408398.2021.1920570. Epub 2021 May 10. PMID: 33970709.
  • Jackson SE, Smith L, Firth J, Grabovac I, Soysal P, Koyanagi A, Hu L, Stubbs B, Demurtas J, Veronese N, Zhu X, Yang L. Is there a relationship between chocolate consumption and symptoms of depression? A cross-sectional survey of 13,626 US adults. Depress Anxiety. 2019 Oct;36(10):987-995. doi: 10.1002/da.22950. Epub 2019 Jul 29. PMID: 31356717.
  • Ludovici V, Barthelmes J, Nägele MP, Enseleit F, Ferri C, Flammer AJ, Ruschitzka F, Sudano I. Cocoa, Blood Pressure, and Vascular Function. Front Nutr. 2017 Aug 2;4:36. doi: 10.3389/fnut.2017.00036. PMID: 28824916; PMCID: PMC5539137.
  • Lin X, Zhang I, Li A, Manson JE, Sesso HD, Wang L, Liu S. Cocoa Flavanol Intake and Biomarkers for Cardiometabolic Health: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J Nutr. 2016 Nov;146(11):2325-2333. doi: 10.3945/jn.116.237644. Epub 2016 Sep 28. PMID: 27683874; PMCID: PMC5086796.
  • De Araujo QR, Gattward JN, Almoosawi S, Silva Md, Dantas PA, De Araujo Júnior QR. Cocoa and Human Health: From Head to Foot–A Review. Crit Rev Food Sci Nutr. 2016;56(1):1-12. doi: 10.1080/10408398.2012.657921. PMID: 24915376.
  • De Araujo QR, Gattward JN, Almoosawi S, Silva Md, Dantas PA, De Araujo Júnior QR. Cocoa and Human Health: From Head to Foot–A Review. Crit Rev Food Sci Nutr. 2016;56(1):1-12. doi: 10.1080/10408398.2012.657921. PMID: 24915376.
  • Zhao B, Gan L, Yu K, Männistö S, Huang J, Albanes D. Relationship between chocolate consumption and overall and cause-specific mortality, systematic review and updated meta-analysis. Eur J Epidemiol. 2022 Apr;37(4):321-333. doi: 10.1007/s10654-022-00858-5. Epub 2022 Apr 23. PMID: 35460393; PMCID: PMC11329947.
  • Ried K, Fakler P, Stocks NP. Effect of cocoa on blood pressure. Cochrane Database Syst Rev. 2017 Apr 25;4(4):CD008893. doi: 10.1002/14651858.CD008893.pub3. PMID: 28439881; PMCID: PMC6478304.
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