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What is Science Based Fitness?

Your free- source of information, news, and deep dive into the latest science in the world or fitness and health. We dive deep into the literature and debunk a lot of fake claims. Also, providing helpful tips and workouts to improve your health and quality of life. 

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Saffron

What are the health benefits of Saffron? 

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Saffron

Possible cure for depression?

Saffron is a very costly spice, and also known as Saffron Crocus. An increasing number of studies shows a lot of benefits for saffron. More randomize, double-blind, placebo control trials are showing promising results in overall health including inflammation, stress, anxiety, depression, cancer prevention, increase libido, and weight loss. 

Known as the sunshine spice due it’s distant color and mood enhancing affects. Saffron is also a very powerful anti-oxidant, which may help prevent many different types of cancers.  Supplementing with 60mg of Saffron for 12 weeks shown significant reduction in weight, fasting triglycerides and increase fasting HDL levels. Saffron constitutes a promising nutraceutical option for adolescents and children with obesity and prediabetes. 

Saffron could be an alternative to other SSRI medications in reducing anxiety and depression symptoms with little to no side effects. More large scale data is required to prove saffron is similar to an SSRI. 

Saffron may play a crucial role in male reproductive health and erectile dysfunction. Although prediabetes is a major risk factor erectile dysfunction, saffron may have aphrodisiac-like properties. 

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Enhance mood

Studies show that saffron may improve mood and sleep. 

Decrease inflammation

Among active young adults, Saffron has been shown in improve recovery and make workouts more enjoyable in males. 

Help with weight loss

Saffron may help reduce appetite, body mass index, waist circumference and fat mass. 

Science Based Review

We highly recommend the benefits of saffron with turmeric. 

The combination of saffron with the benefits and anti-inflammation properties of turmeric delivers the best potential of decreased inflammation elevated mood.
  • Saffron for mood and anxiety
  • Turmeric for treating inflammation
  • Cinnamon for weight loss
  • Cardamom for breathing and oxygen use

Saffron + Turmeric

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Turmeric

Major benefits for brain and body health

Turmeric contains compounds called curcuminoids that’s been shown to reduce inflammation and pain. The most popular curcuminoid is curcumin, and it’s the main active ingredient in turmeric. 

Cinnamon

Anti-inflammatory, aid in metabolic disease and help lose weight

Cinnamon is a spice that’s been shown to improve cardiovascular biomarkers. There’s evidence to show that cinnamon is rich in polyphenols, and may have a beneficial effect on cardio metabolic health, cholesterol, stress and inflammation. 

Cardamom

May help with high blood pressure, weight loss, and infection

Cardamom may help lower blood pressure, improve digestive issues, and help immune function. Research shows a protective compound found in cardamom may help prevent cancers cells from forming or developing. When cardamom is paired with turmeric, data found the combination to be even more effective at preventing tumor growth. 

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References

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  • Tóth B, Hegyi P, Lantos T, Szakács Z, Kerémi B, Varga G, Tenk J, Pétervári E, Balaskó M, Rumbus Z, Rakonczay Z, Bálint ER, Kiss T, Csupor D. The Efficacy of Saffron in the Treatment of Mild to Moderate Depression: A Meta-analysis. Planta Med. 2019 Jan;85(1):24-31. doi: 10.1055/a-0660-9565. Epub 2018 Jul 23. PMID: 30036891.
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  • Shafiee M, Arekhi S, Omranzadeh A, Sahebkar A. Saffron in the treatment of depression, anxiety and other mental disorders: Current evidence and potential mechanisms of action. J Affect Disord. 2018 Feb;227:330-337. doi: 10.1016/j.jad.2017.11.020. Epub 2017 Nov 7. PMID: 29136602.
  • Seyedi-Sahebari S, Farhang S, Araj-Khodaei M, Akhondzadeh S, Naseri A, Sanaie S, Frounchi N. The Effects of Crocus sativus (Saffron) on ADHD: A Systematic Review. J Atten Disord. 2024 Jan;28(1):14-24. doi: 10.1177/10870547231203176. Epub 2023 Oct 21. PMID: 37864351.
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  • Cerdá-Bernad D, Costa L, Serra AT, Bronze MR, Valero-Cases E, Pérez-Llamas F, Candela ME, Arnao MB, Barberán FT, Villalba RG, García-Conesa MT, Frutos MJ. Saffron against Neuro-Cognitive Disorders: An Overview of Its Main Bioactive Compounds, Their Metabolic Fate and Potential Mechanisms of Neurological Protection. Nutrients. 2022 Dec 17;14(24):5368. doi: 10.3390/nu14245368. PMID: 36558528; PMCID: PMC9781906.
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  • Lopresti AL, Smith SJ. An examination into the mental and physical effects of a saffron extract (affron®) in recreationally-active adults: A randomized, double-blind, placebo-controlled study. J Int Soc Sports Nutr. 2022 Jun 7;19(1):219-238. doi: 10.1080/15502783.2022.2083455. PMID: 35813851; PMCID: PMC9261746.
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  • Maierean SM, Serban MC, Sahebkar A, Ursoniu S, Serban A, Penson P, Banach M; Lipid and Blood Pressure Meta-analysis Collaboration (LBPMC) Group. The effects of cinnamon supplementation on blood lipid concentrations: A systematic review and meta-analysis. J Clin Lipidol. 2017 Nov-Dec;11(6):1393-1406. doi: 10.1016/j.jacl.2017.08.004. Epub 2017 Aug 12. PMID: 28887086.
  • Verma SK, Jain V, Katewa SS. Blood pressure lowering, fibrinolysis enhancing and antioxidant activities of cardamom (Elettaria cardamomum). Indian J Biochem Biophys. 2009 Dec;46(6):503-6. PMID: 20361714.
  • Das I, Acharya A, Berry DL, Sen S, Williams E, Permaul E, Sengupta A, Bhattacharya S, Saha T. Antioxidative effects of the spice cardamom against non-melanoma skin cancer by modulating nuclear factor erythroid-2-related factor 2 and NF-κB signalling pathways. Br J Nutr. 2012 Sep 28;108(6):984-97. doi: 10.1017/S0007114511006283. Epub 2011 Dec 19. PMID: 22182368.
  • Majdalawieh AF, Carr RI. In vitro investigation of the potential immunomodulatory and anti-cancer activities of black pepper (Piper nigrum) and cardamom (Elettaria cardamomum). J Med Food. 2010 Apr;13(2):371-81. doi: 10.1089/jmf.2009.1131. PMID: 20210607